Research Areas:

Multimodality imaging
FPGA-accelerated computing
3D Ultrasound imaging
Real-time tumor tracking
Image segmentation / shape reconstruction
Visualization

 



Multimodality imaging

Brain
PET differentiates viable tumors from necrotic masses more accurately than CT and MRI. CT and MRI depict anatomical information more precisely than PET. We fuse CT, MRI and PET with the goal of improving gamma-knife surgery and other radiotherapies/radiosurgeries.

Heart
SPECT and CT images of the heart provide complementary perfusion and structural information. Cardiac images are 4D (3D space + time), and we developed algorithms to fuse following both temporal and spatial registration.

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Body
PET and CT are truly complementary, so much so that medical imaging vendors manufacture combined PET/CT scanners. We can elastically register body PET and CT, whether from stand-alone or from combined scanners.

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FPGA-accelerated computing

Image registration
Automatic image registration usually is slow. FAIR and FAIR-II architectures (FAIR stands for fast automatic image registration) we have developed are allow performing rigid and elastic image registration in real time. A custom board that implemented FAIR architecture is shown below.

CT Reconstruction
CT image reconstruction speed remains a problem. A reconfigurable system-on-chip architecture with parallel data-driven deep pipeline execution units was designed for large-scale parallel computations. This accelerated FDK cone-beam CT reconstruction by a factor of 60. The architecture can also be adapted to other 3D imaging applications.

Preprocessing
3D ultrasound is currently the only real-time 3D medical imaging modality available. Because of its characteristic high level of speckle noise, it is necessary to perform preprocessing at acquisition rates. We have developed FPGA-based architectures for real-time preprocessing of 3D ultrasound using median filtering or anisotropic diffusion filtering.

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3D Ultrasound imaging

Coming soon!

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Real-time tumor tracking

Coming soon!

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Image segmentation / Shape reconstruction

Medical image segmentation is the process of outlining organ boundaries in medical images, and is useful for organ shape reconstruction, visualization and clinical decision making.

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Visualization

One way to visualize large 3D and 4D (3D shape + time) data sets on desktop PCs is to use the GPU in addition to the CPU. Click below to see an interactive exploration of 4D cardiac ultrasound image using GPU-based computing.

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